Desmond Miles is a cynical, 25-year-old bartender and the true protagonist of Assassin's Creed, Assassin's Creed II and Assassin's Creed: Brotherhood. He is an introvert, that has to do with his weird youth.

Desmond has an undeniable resemblance to Altaïr Ibn La-Ahad and Ezio Auditore da Firenze. The former bartender wears no fancy clothes, just a white hooded sweatshirt, jeans and white sneakers. It is interesting that Desmond's hood pulled back approximately similar to that of Altaïr and Ezio. Another similarity between the three men is the scar on his mouth, which is particularly noticeable when Ezio through his beard, but on closer inspection, even when Desmond and Altair is visible.

Desmond is a harsh and cynical loner who has a serious view of life, caused by the conflict between the Assassins and Templars in his youth.