Brian Leslie Blair was born on January 12, 1957, in Gary, Indiana, United States. After graduating from Hillsborough High School in Tampa, Florida at the age of 17, Blair started training in the summer for Championship Wrestling from Florida (CWF). Blair attended Saint Leo College near Dade City, then transferred to the University of Louisville on a football scholarship, and majored in both business and political science.

In the summer months from 1975–1977 Blair started training to be a wrestler with Hiro Matsuda in Florida. Blair debuted in 1977 with Eddie Graham's CWF where he worked primarily as a face. Blair debuted in a tag team match facing Pat Patterson and Ivan Koloff. One of Blair's early opponents was another Matsuda student later known as Hulk Hogan. He also appeared regularly for Leroy McGuirk's Tri-State promotion, here he met and married Leroy McGuirk's daughter Mike McGuirk in 1980. He was even shot at by Leroy when he tried to talk to Mike before leaving town. After leaving the Tri-State promotion Blair joined up with Fritz Von Erich's World Class Championship Wrestling promotion in Texas, where he lived with David Von Erich for over a year.

The Killer Bees were a tag team composed of "Jumpin" Jim Brunzell and Blair in the World Wrestling Federation from 1985 to 1988. The two men were signed by the WWF as it continued its national expansion through 1985. The name was inspired by the 1972 Dolphins' linebackers, whose names all began with the letter B and were the first to use the moniker. Blair was already a part of the company, wrestling as a singles competitor in 1984, mostly as "enhancement talent", but previously being a mid-card wrestler during 1980 and 1983. The teaming of Blair and Brunzell was suggested by Hulk Hogan. Because Blair and Brunzell were similar in build, the team had a special gimmick referred to as "masked confusion" where both wrestlers would put on identical masks during matches to confuse the opponents and referee and usually win that way—despite this normally being a tactic used by heels. The “masked confusion" idea was given to Blair by Billy Red Lyons. The team debuted on June 17, 1985, defeating the team of Steve Lombardi and Dave Barbie. This was also Brunzell's first match in the WWF.

One of the most amusing highlights of the team's career came in 1987 at a house show at the California University of Pennsylvania. With Blair unable to appear for the team's match against Demolition, he was replaced by S. D. Jones, an African-American journeyman who wore the Bees' black and yellow tights for the day. During the match, the two used the "masked confusion" tactic and the referee, as usual, pretended to be unable to tell the two apart, despite Brunzell being very light-skinned. The inverse would occur later, as Jones replaced Brunzell and teamed up with Blair in a Prime Time Wrestling TV taping, against Demolition.

In the summer of 1988 the Bees split up off-screen without any break up or announcement, and Brunzell and Blair returned, being used as "preliminary wrestlers" thus ending the yellow and black days of the Bees. The duo's last WWF match as a team came on August 24, 1988, against the Young Stallions.

Blair is married to Toni Sabella and they have two sons. Blair owned and managed four Gold's Gym fitness centers in the Tampa Bay area with fellow wrestler, Steve Keirn. They were sold in 1999 for $2.1 million. Blair is now the President and CEO of the 501c3 Cauliflower alley Club. The Cauliflower Alley Club (CAC) gives financial assistance to people from the wrestling Industry who have fallen on difficult times.

This skin was made for me by Yondee.