Its possible, but the only problem is the Massive Competition when it comes to lets plays.
If your planning to do a Lets Play, do a Unique map that others havent played before, well at least one the big Youtubers havent done yet. If you also add a sence of uniqueness to your videos and such, well, you could become famous on youtube. Take in mind that all the big youtubers when Related to minecraft are unique in their own ways. For example SethBling is a Redstone God, he makes unmeasurably amazing redstone Contraptions that everyone wants to own in their Survival World, or Hypixel with his maps, or Antvenom, SkythekidRS, Cavemanfilms with their Adventure Map playthroughs, Minigame livestreams and Lets plays, with a Sence of Humor in them.
Take that to consideration.
[Ninja'd] True, people go for Commentaries now, especially humerous ones.
