i can handle creepers anyday, sure they blow my things up, but i can rebuild. there annoying as hell.. but i hate the skeletons the most because thy are long rang, every time the fire there arrow i almost jump out of my pants just from that sound, and evey can attack threw openings in blocks, so if ur looking down at one and they hit u, u can fall down with them, or even die... xD
so i say Skeletons.. xD