Palazzo del Refugio is a Palace in Livorno, Italy. It is located on the navicelli canal in Livorno, Toscana, Italy. It is close to the Piazza del Luogo Pio aswell as the dominican church (Santa Caterina da Siena) . Right next to this palace is the Palace Palazzo dei Domenicani aswell as the Orphanage.

The building was build in the year 1755 in Late baroque style and was finished 1758.

In the 19th century the building housed the School of Architecture.

During the second world war the Americans have destroyed a part of this buildings which lays now in ruins, due to the Violent aerial bombardement of Livorno.